LIQUIDATOR96®

Manual pipetting in perfection.

With its 96 pipetting channels, the purely manual LIQUIDATOR96® is predestined for pipetting 96-well or 384-well plates. With its incredible precision, great flexibility and very simple and intuitive operation, it is already delighting thousands of laboratory staff all over the world.
In Germany Steinbrenner Laborsysteme GmbH is the sole supplier of the instrument, in all other countries the distribution is done by our licensee METTLER TOLEDO.

Wide range of applications .

PCR and qPCR

ELISA / Enzymatic Assays

Protein Crystallization

Luminex Assays

Active substance screenings

Sequencing

Cell culture

siRNA Screenings

FACS / Microscopy

Genotyping

DNA/RNA purification

Yeast 2 Hybrid

Applications .

Fill plates, present solutions, add reagents

Protein crystallization: transfer of crystallization buffer – typically 70-80 µl – from deep-well plate into special protein crystallization plates.
ELISA or other time-critical assays: pipette samples into a 96-well plate – add substrate, conjugate and stop solutions simultaneously to all 96 wells.
PCR/qPCR/RT-qPCR: Pipetting of nucleic acid template into 96-/384-well PCR plate; addition of PCR/qPCR Master Mix.
si-RNA-/cDNA- Library Screening: Aliquoting and dilutions of siRNA and cDNA libraries, preparation of DNA/siRNA transfection mixes, addition of staining solution.
FACS assays: various washing steps with cells in 96-well plates.
Fast preparation of source plates, e.g. deep wells for the start of an automation process on robots or for general acceleration of the robotic process.

Repipetition/ reformatting or duplication of plates

High Content Screening (HCS) e.g. with yeast cells: Preparation of 96-well daughter plates, addition of medium, removal of supernatant, washing of cells from supernatant, transfer of e.g. 50 µl cell suspension into a special 384-well microscope plate in only 4 steps.
Corona detection: transfer of a few microliters of extracted viral RNA from a 96-well plate into a 384-well PCR plate for analysis by RT-qPCR.
NGS sequencing of gut microbiome samples: DNA extraction using magnetic beads, many 96-fold pipetting steps (additions of binding and elution buffer, several washing steps), transfer of DNA/RNA into the NGS process.
Sequencing/genotyping: pipetting and washing steps in the context of DNA extraction from e.g. mouse tails or ear punches in 96 format using filter plates or magnetic bead kits.
Antibiotic screening: production of 96-well antibiotic daughter plates.

Remove protrusions

Pipetting of cell suspensions, compounds, removal of supernatants, preparation of dilutions in the context of drug screening with a wide variety of cell assays such as cell binding studies, cell proliferation assays or cytotoxicity assays.

Sow cells

Cell culture: seeding of cells, medium change, removal of supernatants.

Drop

Antibiotic screening: settling a 1 µl drop into a daughter plate, adding bacterial solutions.
Settling of small drops on a surface (e.g. glass, chip).

Features .

System comparison .

The LIQUIDATOR96® closes the gap between manual and automated liquid handling. It is also an ideal addition to an existing automation system, as it perfectly combines the strengths of multichannel pipettes and pipetting robots.

Fast and safe pipetting of 96- and 384-well plates
Much faster and safer than a multichannel pipette
Minimal training required due to intuitive operation
In many cases faster than a pipetting robot
Simultaneous pipetting of up to 96 samples
4 precisely approachable working positions
Precisely guided pipetting head with adjustable lowering depth

Play Video

Error reduction .

Pipetting multiwell plates with single- and multi-channel pipettes is strenuous and error-prone. It is very easy to omit individual wells or entire rows or to accidentally pipette twice. This does not happen with the LIQUIDATOR96®!

Due to the precise guidance of the pipetting head, the tips also always hit the correct wells, without any aiming. This means that 384-well plates can also be pipetted effortlessly and safely in just 4 steps using an adapter – with very little pipetting variance.

Speed .

Unpack and get started. Unlike complicated pipetting robots, the LIQUIDATOR96® can be used efficiently in the laboratory after only a brief introduction.

Its four working positions can be precisely approached, which significantly speeds up pipetting work and makes it much safer and more convenient than using a multichannel pipette.

Precision .

Patented technology

The LIQUIDATOR96® achieves excellent precision and pipetting homogeneity over all 96 channels due to its patented volume control mechanics.

Two device versions

The LIQUIDATOR96®-200 covers the range of 5 (3) – 200 µl, whereas the LIQUIDATOR96®-20 is perfect for small volumes from 0.5 – 20 µl.

	20 μl instrument	200 μl instrument
Volume range	0.5 – 20 μl	3 – 200 μl
Random measurement error (precision)	20 μl: ± 0.8 %	200 μl: ± 0.5 %
	10 μl: ± 1.0 %	100 μl: ± 0.8 %
	2 μl: ± 5.0 %	20 μl: ± 1.5 %
	1 μl: ± 10.0 %	5 μl: ± 3.5 %
Systematic measurement error (accuracy)	20 μl: ± 1.0 %	200 μl: ± 1.0 %
	10 μl: ± 1.2 %	100 μl: ± 1.0 %
	2 μl: ± 6.0 %	20 μl: ± 2.0 %
	1 μl: ± 12.0 %	5 μl: ± 5.0 %
Setting steps for volume	0.1 μl	0.1 μl
Suitable plate formats	96 and 384 well	96 and 384 well
SBS working positions	4	4
Power supply/battery	no power required	no power required
Dimensions (LxWxH, in cm)	37 x 46 x 41	37 x 46 x 41
Weight	approx. 14.5 kg	approx. 15 kg
Item number	SL-LIQ96RT-20	SL-LIQ96RT-200

Safety .

Flexibility and efficiency .

No installation and no mains connection required
Transportable and compact, also fits under the sterile bench or fume hood
Simplest integration into existing processes and workflows
Manual control also enables tricky pipetting steps
Large volume range from 0.5 μL to 200 μL covered by two instrument versions

The LIQUIDATOR96® in action .

Below you will find some videos on how to operate the LIQUIDATOR96®.

The best thing is to make yourself a picture! We would be happy to present the device to you during a non-binding and free demo on site and show you how you can efficiently integrate the LIQUIDATOR96® into your daily laboratory routine.

The comfort adapter for processing 384-well plates .

Our comfort adapter makes processing 384 plates with the LIQUIDATOR96® even more convenient and safe. With its joystick-controlled shifting mechanism, the four 96 quadrants of a 384-well plate can be precisely approached. The graphic and alphanumeric position display shows you exactly which quadrant is currently being pipetted.

Art. No. SL-Liq-A384C