Sample collection for the diagnostic of infectious diseases .
The DNA Genotek OMNIgene ORAL or Colli-Pee® kits are easy to handle and therefore also ideally suited for home use. Since the DNA and RNA remain stable in the tube up to +50°C, no cold chain is required.
Hard Facts .
OMNIgene ORAL products provide a painless, non-invasive alternative to blood collection for the detection of circulating Plasmodium falciparum or P. vivax parasites.
Okumu, W., Okeyo, W. A., Munde, E. O., Raballah, E., Anyona, S. B., & Ouma, C. (2015). Evaluation of saliva-derived Plasmodium falciparum DNA using the OMNIgene®-ORAL kit in detection of malaria. DNA Genotek https://www.dnagenotek.com/ROW/pdf/PD-WP-00035.pdf
Visanuvimol, D. (2014). Saliva as a proven, non-invasive sample type for molecular malaria testing and surveillance using OMNIgene®-ORAL at ambient temperatures. DNA Genotek https://www.dnagenotek.com/ROW/pdf/PD-WP-00041.pdf
The gold standard for detecting SARS-CoV-2 infection is the detection of viral RNA in saliva samples or oral, pharyngeal, and nasal swabs by PCR/qPCR. The OMNIgene ORAL Kit OME-505 stabilizes SARS-CoV-2 RNA in collected saliva samples over several weeks at room temperature and allows home sample collection.
DNA Genotek. (2020). Inactivation of SARS-CoV-2 in samples collected using Oragene®, ORAcollect® and OMNIgene® products from DNA GenotekTM. https://www.dnagenotek.com/ROW/pdf/MK-01430.pdf
Colameco, S., Brown, A., & Crawford Parks, T. (2020). Ambient temperature stabilization of SARS-CoV-2 viral RNA in OMNIgene®-ORAL (OME-505) collected saliva samples. DNA Genotek https://www.dnagenotek.com/ROW/pdf/PD-WP-00069.pdf
Stabilization of viral DNA and RNA after sample collection is important to obtain results of consistent quality and to avoid bias. The OME-505 kit (formerly OM-505) allows long storage time of up to three weeks at room temperature without loss of DNA or RNA quality.
DNA Genotek. (2015). OMNIgene®-ORAL (OM-505) stabilizes RNA from human viruses at room temperature for several weeks. https://www.dnagenotek.com/ROW/pdf/PD-WP-00024.pdf
Doukhanine, E., & Merino, C. (2020). Stability, recovery efficiency and detection limit of viral DNA in OMNIgene®-ORAL (OM-505). DNA Genotek https://www.dnagenotek.com/ROW/pdf/PD-WP-00028.pdf
Molecular detection of human papillomavirus (HPV) DNA in urine is suitable for screening for cervical precancerous lesions. Colli-Pee® enables user-friendly self-collection of urine, eliminating the need for cervical swabs for cytological analysis.
Mehta, A., Laeremans, M., Meers, N., Ríos Cortés, A., Van Avondt, Q., Pasmans, D., Beyers, K., & Vankerckhoven, V. (2021). First-void urine as a game-changer for HPV-based cervical cancer screening. Novosanis. Link
Laeremans, M., Mehta, A., Pasmans, D., Jordaens, S., Faster, D., Beyers, K., & Vankerckhoven, V. (2021). HPV-based cervical cancer screening: gaining insights into sample preference and cost-effectiveness. DNA Genotek Link
Pasmans, D., Mehta, A., Bruyninckx, S., Hendrickx, J., Beyers, K., & Vankerckhoven, V. (2021). Molecular-based triage on hrHPV-positive women to detect cervical cancer. DNA Genotek Link
First urine is suitable for detecting pathogen DNA of sexually transmitted infectious diseases (STIs), including human papillomavirus (HPV) and Chlamydia trachomatis (CT).
Mehta, A., Pasmans, D., Vankerckhoven, V., & Beyers, K. (2021). Urine collected through Colli-Pee offers potential for self-sampling at home for detection of sexually transmitted infections. Novosanis. Link