Magnetic Beads
One principle for many applications.
Magnetic beads are true all-rounders in everyday biological and medical laboratory work.
By functionalizing the surface, they can be specifically optimized for the desired application. This property makes them versatile, for example for purification of biomolecules such as nucleic acids, proteins, coupling of antibodies, isolation of cells or size selection in NGS.
We offer Magnetic Beads and extraction kits from our partner Magtivio BV.
Wide range of applications .
DNA & RNA Purification
Protein purification
LC-MS/MS Sample preparation
PCR purification
High throughput
Streptavidin-based purification
Functional surface
Easy-to-use, low cost
Uncomplicated .
- Simple workflow - Bind, Wash, Elute
- Everything can be carried out in one reaction vessel
- Automated workflow enables high throughput
- No Centrifugation needed
- Versatile use thanks to different surface modifications
Overview Magnetic Beads .
- NGS and PCR purification
- Dye Terminator Removal at Sanger Sequencing
- Extraction / purification of genomic DNA from various sample materials
- Extraction / purification of RNA from various sample materials
- Purification of circulating cell-free DNA (cfDNA)
- Purification of peptides and proteins
- Sample preparation of LC/MS applications
- Coupling peptides
- Coupling proteins
- Coupling of nucleic acids
- Coupling antibodies
- Coupling of biomolecules
Products | Product category | Analyte | Application | Remarks |
---|---|---|---|---|
MagSi-DNA Beads | DNA isolation | DNA | Isolation of nucleic acids | Different bead sizes and surface modifications available |
MagSi-DT Removal | PCR and NGS purification | DNA | Removal of dye terminators from sequencing reactions | |
MagSi-NGSPREP Plus | PCR and NGS purification | DNA | PCR clean-up and size selection for library preparation | |
MagSi-STA Beads | Streptavidin-coupled beads | Biotinylated molecules | Immunoassays, capture and purification of biotinylated molecules | Different bead sizes and surface modifications available |
MagSi-Proteomics | Protein purification | Proteins / peptides | Protein purification, proteome profiling, biomarker research | Magnetic beads with C4, C8 or C18 alkyl chains as surface modification |
MagSi-WCX | Protein purification | Proteins / peptides | Reduction of protein / peptide complexity, sample preparation and pre-fractionation for SDS-PAGE analysis and mass spectrometry | Magnetic beads with weak cation exchange (WCX) surface |
MagSi-WAX | Protein purification | Proteins / peptides | Reduction of protein / peptide complexity, sample preparation and pre-fractionation for SDS-PAGE analysis and mass spectrometry | Magnetic Beads with weak anion exchange (WAX) surface |
MagSi-Protein A / G | Protein purification | Immunoglobulins | Immunoassays, immunoprecipitation, Ig purification | Magnetic beads with covalently bound protein A or protein G. Different bead sizes available |
MagSi-S Beads | Functionalized beads | Proteins, peptides, nucleic acids, other molecules | Coupling of target molecules to bead surface | Different bead sizes and surface modifications available – including COOH, NH2, SH, CHO, tosyl, hydrazide and epoxy |
MagSi-DX Pathogen / MagSi-NA Pathogen | Pathogen Detection DNA Isolation | DNA / RNA | Isolation of pathogenic DNA / RNA from various sample materials | |
MagSi-DNA Body Fluid | DNA isolation | DNA | Isolation of genomic DNA from blood, saliva or swab samples | |
MagSi-DNA Tissue & Cells | DNA isolation | DNA | Isolation of genomic DNA from animal tissue samples and euraryotic cells. | |
MagSi-DNA Animal | DNA isolation | DNA | Isolation of genomic DNA from animal samples such as blood, semen, hair, saliva, swabs, or lysed tissues | |
MagSi-DNA Vegetal | DNA isolation | DNA | Isolation of genomic DNA from plant samples | Specialized kits that are either more suitable for DNA isolation from plant seeds or leaf samples |
MagSi-cfDNA | DNA isolation | DNA | Isolation of cell-free circulating DNA from human plasma or serum samples | |
MagSi-DNA FFPE | DNA isolation | DNA | Isolation of genomic DNA from FFPE-embedded mammalian tissue or cell samples |
Application examples for Magnetic Beads .
DNA isolation
from saliva, sputum, blood samples as well as plant material
Pathogen detection
Purification of DNA/RNA for in vitro diagnosis of pathogens
cfDNA isolation
Isolation of circulating cell-free DNA (cfDNA) from plasma or serum.
Protein isolation
Purification of peptides and proteins
Functional beads
Silica beads with differently functionalized surface
Streptavidin-coupled beads
Purification of biotinylated molecules.
LC/MS applications
Sample preparation for LC/MS by negative selection
Accessories
Magnet racks and magnetic disks